Prostatitis and PSA
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is a common male's urology and reproductive system disease affects men
in 20s to 50s, it is an inflammation of the prostate gland. The full
name PSA is prostate-specific antigen, is also known as
gamma-seminoprotein or kallikrein-3, is a glycoprotein enzyme encoded in
human by the epithelial cells of the prostate gland.
PSA is
present in small quantities in the serum of men with healthy prostates,
but is often elevated in the presence of the prostate cancer or other
prostate disorders. PSA is not a unique indicator of prostate cancer,
but may also detect prostatitis or benign prostatic hyperplasia. So what
a high level PSA means if it is not a prostate cancer?
1. PSA level may change as age changes
Even without any prostate problems, the PSA level of a man can go up
gradually as his age. A urologist in Chicago area whose name is John
Milner, MD says: "At age 40, a PSA of 2.5 is the normal limit, by age
60, the limit is up to 4.5; by age 70, a PSA could be considered
normal." So it may be normal for a man who finds his PSA level is higher
than that of last year.
2. Medical Procedures Can Cause PSA to Rise
Anything that traumatically interferes with the surrounding positions
of the prostate gland can make PSA go up. One of the most common causes
of significantly high PSA from this type of trauma is the placing of a
catheter into the bladder. Another cause is a prostate or bladder exam
that involves passing a scope or taking a biopsy. Since it takes about
two to three days for PSA to go down by half, a man should wait two to
three weeks after this type of trauma to do a PSA test.
3. BPH In Men Over 50 May Be the Cause of High PSA
Benign prostatic hyperplasia (BPH) is an enlargement of the prostate
gland, but it’s not prostate cancer. BPH means more cells, so that means
more cells making PSA, BPH is the most common prostate problem in men
over age 50. It may not need to be treated unless it’s causing frequent
or difficult urination. A primary care doctor may be able to tell the
difference between BPH and prostate cancer by doing a digital rectal
exam, but commonly this will require evaluation by a urologist and
further testing, such as a biopsy or imaging studies.
4. High PSA Levels From a Urinary Tract Infection
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Any infection near the prostate gland, including a urinary tract
infection, can irritate and inflame prostate cells and cause PSA to go
up. If a man has been diagnosed with a urinary tract infection, he must
be sure to wait until after the infection has cleared up before he gets a
PSA test. In men, most urinary tract infections are caused by bacteria
and respond well to antibiotics. Having BPH increases the risk for a
urinary tract infection.
5. Ejaculation Is a Potential Cause of Mildly Elevated PSA
"Ejaculation can cause a mild elevation of your PSA level, and so can
having a digital rectal exam," says Milner. "These types of PSA
elevations are usually not enough to make a significant difference
unless your PSA is borderline. PSA should return to normal in two to
three days."
To avoid this type of elevation, doctors will usually
draw blood for a person's PSA level before doing a rectal exam. Ask
your doctor if you should avoid ejaculation for a few days before a PSA
test.
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